Langerhans Cell Mobilization Distinguishes between Early-Onset and Late-Onset Psoriasis
نویسندگان
چکیده
منابع مشابه
Solitary, late-onset, self-healing Langerhans cell histiocytosis.
© 2011 The Authors. doi: 10.2340/00015555-0990 Journal Compilation © 2011 Acta Dermato-Venereologica. ISSN 0001-5555 “Self-healing” Langerhans’ cell histiocytosis (LCH), first reported by Hashimoto & Pritzker in 1973 (1), is a rare primary skin disorder that presents at birth or just after birth. It can be categorized based on the involvement of solitary or multiple sites and can be further cla...
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BACKGROUND Migration of epidermal Langerhans cells (LCs) in response to the cytokines interleukin (IL)-1β and tumour necrosis factor (TNF)-α is impaired in uninvolved skin of patients with early-onset psoriasis. AIM To investigate whether this impairment is a reflection of a systemic defect in dendritic cells (DCs), using an established model of monocyte-derived LC-like cells (mLCs). METHOD...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2010
ISSN: 0022-202X
DOI: 10.1038/jid.2010.57